ea0028oc3.6 | Obesity, thyroid and Addison's disease | SFEBES2012
Mitchell Anna
, MacArthur Katie
, Gan Earn
, Baggott Lucy
, Wolff Anette
, Skinningsrud Beate
, Short Andrea
, Kampe Olle
, Bensing Sophie
, Betterle Corrado
, Kasperlik-Zaluska Anna
, Czarnocka Barbara
, Fichna Marta
, Hulting Anna-Lena
, Badenhoop Klaus
, Falorni Alberto
, Ollier William
, Undlien Dag
, Husebye Eystein
, Pearce Simon
Autoimmune Addisons disease (AAD) is a rare, highly heritable endocrinopathy with an estimated λsibling (ratio of risk to a sibling vs the unrelated background population) of 160210. The majority of the genetic risk to AAD has yet to be accounted for. We have used a tag-SNP approach to seek association between single nucleotide polymorphisms (SNPs) in the GATA3 gene and autoimmune Addisons disease (AAD). 2001 AAD cases and 1898 controls were included in ...